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Total 518 results found since Jan 2013.

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of < em > Dabie bandavirus < /em > in aged ferrets
This study demonstrates that DBV GnH-FT nanoparticles provide an efficient vaccine efficacy in mouse and aged ferret models and should be an outstanding vaccine candidate targeted for the aged population against fatal DBV infection. IMPORTANCE Dabie bandavirus (DBV) is an emerging tick-borne virus that causes severe fever with thrombocytopenia syndrome (SFTS) in infected patients. Human SFTS symptoms progress from fever, fatigue, and muscle pain to the depletion of white blood cells and platelets with fatality rates up to 30%. The recent spread of its vector tick to over 20 states in the United States increases the potenti...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Dokyun Kim Eunha Kim Semi Kim Youseung Chung Chih-Jen Lai Inho Cha Sung-Dong Cho Yunseo Choi Xinghong Dai Stephanie Kim Seokmin Kang Mi-Jeong Kwak Ziyi Liu Younho Choi Su-Hyung Park Young Ki Choi Jae U Jung Source Type: research

Vaccination Coverage Among Adolescents Aged 13-17 Years - National Immunization Survey-Teen, United States, 2022
MMWR Morb Mortal Wkly Rep. 2023 Aug 25;72(34):912-919. doi: 10.15585/mmwr.mm7234a3.ABSTRACTThree vaccines are routinely recommended for adolescents to prevent pertussis, meningococcal disease, and cancers caused by human papillomavirus (HPV). CDC analyzed data from the 2022 National Immunization Survey-Teen for 16,043 adolescents aged 13-17 years to assess vaccination coverage. Birth cohort analyses were conducted to assess trends in vaccination coverage by age 13 years (i.e., before the 13th birthday) and by age 14 years (i.e., before the 14th birthday) among adolescents who were due for routine vaccination before and dur...
Source: MMWR Morb Mortal Wkl... - August 24, 2023 Category: Epidemiology Authors: Cassandra Pingali David Yankey Laurie D Elam-Evans Lauri E Markowitz Madeleine R Valier Benjamin Fredua Samuel J Crowe Carla L DeSisto Shannon Stokley James A Singleton Source Type: research

United States' regulatory approved pharmacotherapies for nuclear reactor explosions and anthrax-associated bioterrorism
Expert Opin Drug Saf. 2023 Aug 18:1-6. doi: 10.1080/14740338.2023.2245748. Online ahead of print.ABSTRACTINTRODUCTION: Nuclear reactor incidents and bioterrorism outbreaks are concerning public health disasters. Little is known about US Food and Drug Administration (FDA)-approved agents that can mitigate consequences of these events. We review FDA data supporting regulatory approvals of these agents.AREAS COVERED: We reviewed pharmaceutical products approved to treat Hematopoietic Acute Radiation Syndrome (H-ARS) and to treat or prevent pulmonary infections following Bacillus anthracis (anthrax) exposure. Four drugs were a...
Source: Expert Opinion on Drug Safety - August 18, 2023 Category: Drugs & Pharmacology Authors: Charles L Bennett Peter Georgantopoulos Robert Peter Gale Kevin Knopf William J Hrushesky Chadi Nabhan James O Armitage Source Type: research

Predictors of Colonoscopy Use Among Asian Indians in New York City, 2003 to 2016
CONCLUSIONS: Among Asian Indians living in New York City, several demographic, socioeconomic, and health-related characteristics predict colonoscopy use. These findings highlight the importance of examining determinants of colonoscopy uptake in this understudied population to inform future public health interventions.PMID:37556383 | DOI:10.1097/MCG.0000000000001900
Source: Clinical Colorectal Cancer - August 9, 2023 Category: Cancer & Oncology Authors: Neha Nagpal Taylor M McCready Yuhe Xia Kevin Lin Matthew Glenn Sandy Ng Chau Trinh-Shevrin Andrea B Troxel Simona C Kwon Peter S Liang Source Type: research

The effectiveness of a religiously framed HPV vaccination message among Christian parents of unvaccinated adolescents in the United States
CONCLUSION: Our findings support the need for equitable messaging regarding HPV vaccination. Faith-based messaging interventions that seek to increase HPV vaccination should be framed to address religious anti-vaccination beliefs.PMID:37401883 | DOI:10.1080/17538068.2023.2171613
Source: Cancer Control - July 4, 2023 Category: Cancer & Oncology Authors: Ayokunle Olagoke Jennifer Hebert-Beirne Brenikki Floyd Rachel Caskey Andrew Boyd Yamil é Molina Source Type: research

Human papillomavirus vaccination at the first opportunity: An overview
Hum Vaccin Immunother. 2023 May 23:2213603. doi: 10.1080/21645515.2023.2213603. Online ahead of print.ABSTRACTThe Advisory Committee on Immunization Practices (ACIP) has recommended human papillomavirus (HPV) vaccination for adolescents in the United States since 2006. Though recommended at a similar time to the routine recommendations for adolescent tetanus, diphtheria, and acellular pertussis vaccination (Tdap) and quadrivalent meningococcal vaccination (MCV4), HPV vaccine uptake has consistently lagged behind these other adolescent vaccines. The ACIP recommends HPV vaccination at 11-12 y, with vaccination starting at 9 ...
Source: Cancer Control - May 23, 2023 Category: Cancer & Oncology Authors: Robert A Bednarczyk Noel T Brewer Melissa B Gilkey Sherri Zorn Rebecca B Perkins Kristin Oliver Debbie Saslow Source Type: research

Influences of sociodemographic characteristics and parental HPV vaccination hesitancy on HPV vaccination coverage in five US states
CONCLUSIONS: Adolescent HPV vaccination coverage remains low in our targeted states. Children's age, sex, and parental vaccine hesitancy were significantly associated with likelihood of HPV vaccination. These findings offer the opportunity for targeted interventions among parents in regions with low vaccine uptake and underscore the importance of developing and implementing strategies to address parental HPV vaccination hesitancy to improve uptake in the US.PMID:37198022 | DOI:10.1016/j.vaccine.2023.04.082
Source: Vaccine - May 17, 2023 Category: Allergy & Immunology Authors: T Shato S Humble A Anandarajah A Barnette H M Brandt J Garbutt L Klesges V S Thompson M I Silver Source Type: research